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M9490329.TXT
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1994-09-19
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Document 0329
DOCN M9490329
TI HIV serosurveillance in Papua New Guinea.
DT 9411
AU O'Leary MJ; van der Meijden WI; Malau C; Delamare O; Pyakalyia T; World
Health Organization, Department of Health, Port Moresby,; Papua New
Guinea.
SO P N G Med J. 1993 Sep;36(3):187-91. Unique Identifier : AIDSLINE
MED/94337533
AB To determine human immunodeficiency virus-1 (HIV-1) prevalence in low-
and high-risk populations in Papua New Guinea (PNG), anonymous unlinked
serosurveillance was conducted in government-administered antenatal and
sexually transmitted disease (STD) clinics at six sites beginning in
June 1989. Although 3 of 1233 samples were HIV positive in a pilot
study, none of 7948 samples was HIV positive during the first full year
of serosurveillance (June 1989--May 1990). HIV-infected people are also
identified in PNG through clinical diagnostic testing. Although
underreporting is probably substantial, 45 HIV-infected people had been
identified in PNG (population 3.6 million) through diagnostic testing
between 1987 and the end of the first serosurveillance year (May 1990).
In view of the steadily emerging clinical problem of acquired immune
deficiency syndrome (AIDS) in PNG, the negative results of
serosurveillance required explanation. Three possibilities are proposed:
1) the sample size chosen could fail to detect a case 5% (or more) of
the time under the likely conditions of this survey; 2) the populations
chosen for surveillance may not, yet, be those in which HIV is
circulating at this early stage of the epidemic in PNG; and 3)
laboratory error could account for some false negative results. The
first two of these, alone or in combination, are most likely. Limited
surveillance continued in PNG in 1991 and 1992. By June of 1992, 5 of an
additional 6035 serosurveillance samples had tested positive. All 5 were
among 2000 samples from a single site, the Port Moresby STD
Clinic.(ABSTRACT TRUNCATED AT 250 WORDS)
DE Adult Bias (Epidemiology) Female Human HIV
Infections/BLOOD/COMPLICATIONS/*EPIDEMIOLOGY *HIV Seroprevalence
*HIV-1 Infant, Newborn Male Papua New Guinea/EPIDEMIOLOGY Pilot
Projects *Population Surveillance Prevalence Risk Factors
Seroepidemiologic Methods Sexually Transmitted
Diseases/COMPLICATIONS/EPIDEMIOLOGY Support, Non-U.S. Gov't JOURNAL
ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).